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2014 Nov 10
J Biomol Screen
Chemical Name: (Z)-2-(4-bromo-2-((4-oxo-3-(pyridin-3-ylmethyl)-2-thioxothiazolidin-5-ylidene)methyl)phenoxy)acetic acid
1956356-56-1
Formula: C26H34ClN6O2P
PF-06826647 Size:100mg solid 2014 Nov 10PF 06826647 (Tyk2 IN 8, compound 10) is a selective and orally administered inhibitor of tyrosine kinase 2 (TYK2) with IC50 of 17 nM for binding to TYK2 catalytically active JH1 domain. PF 06826647 (Tyk2 IN 8, compound 10) also inhibits JAK1 and JAK2 with IC50 of 383 nM and 74 nM, respectively. PF 06826647 (Tyk2 IN 8, compound 10) is used in the treatment of psoriasis (PSO). Product information CAS Number: 2127109 84 4 Molecular Weight: 383. 41
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